THYMOGENIC IMMUNOCORRECTION OF CHILDREN WITH CONGENITAL HEART DEFECTS

Abstract

The prevalence of congenital heart defects CHD at birth was 6.7 per 1,000 live births, with two cases out of five being severe. Immune status indicators were studied in children who were referred to surgical correction of CHD without thymectomy or with thymectomy of varying degrees of completeness. It was found that changes in the normal emigration of T cells from the thymus, in particular under the influence of thymectomy, significantly affect the number of T and B lymphocytes in the blood.Immunomodulatory therapy in children has some features associated primarily with the greater reactivity of the immune system in comparison with the immune system of adults.