THE EFFECT OF CMVI ON THE NERVOUS SYSTEM AND KIDNEYS IN NEWBORNS

Abstract

Intrauterine infections occupy one of the leading places in the structure of perinatal mortality. Cytomegalovirus infection ranks first among congenital infections, making a great contribution to the formation of various malformations. The literature review describes the pathogenetic mechanisms of the virus' effect on the fetus and newborn, kidney organs and the central nervous system. CMVI develops as a result of infection of the mother with the virus or its reactivation, causing the development of infection. When the fetus is infected in the early stages of pregnancy, various malformations of the central nervous system, cardiovascular, urinary systems, etc. are formed. When infected in late pregnancy, infectious lesions of various organs and systems are revealed in newborns. In 40-90% of newborns with manifest CMVI, there are long-term neurological consequences and kidney disease, hearing loss, as well as damage to the organs of vision.